A mixed mirror-image DNA/RNA aptamer inhibits glucagon and acutely improves glucose tolerance in models of type 1 and type 2 diabetes
A Vater, S Sell, P Kaczmarek, C Maasch… - Journal of Biological …, 2013 - ASBMB
... Glucagon (HSQGTFTSDYSKYLDSRRAQDFVQWLMNT) was synthesized as an all-d-peptide
with and ... acid), respectively, to an ethylendiamino spacer at the peptides' C termini ... form (viaPEG2-PEG2-ethylendiamino-linker) were purchased from Bachem (Bubendorf, Switzerland ...
with and ... acid), respectively, to an ethylendiamino spacer at the peptides' C termini ... form (viaPEG2-PEG2-ethylendiamino-linker) were purchased from Bachem (Bubendorf, Switzerland ...
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