Angiotensin-(1-7) attenuates the anxiety and depression-like behaviors in transgenic rats with low brain angiotensinogen

Angiotensin-(1-7) attenuates the anxiety and depression-like behaviors in transgenic rats with low brain angiotensinogen

LM Kangussu, AF Almeida-Santos, M Bader… - Behavioural brain …, 2013 - Elsevier

... All components of the RAS are present in the brain, where angiotensin peptides are mainly
involved in ... like behaviour in the EPM test suggesting an anxiolytic-like effect of this peptide [18 ...
Ang-(1–7) (Bachem ® ) was diluted in sterile saline (2 mg/ml) aliquoted (10 μL) and stored ...

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