Polyphenols can inhibit furin in vitro as a result of the reactivity of their auto-oxidation products to proteins

Polyphenols can inhibit furin in vitro as a result of the reactivity of their auto-oxidation products to proteins

J Zhu, WJM Van de Ven, T Verbiest… - Current medicinal …, 2013 - ingentaconnect.com

... Casein was obtained from Merck. The furin inhibi- tor nona-D-arginine (D9R) was obtained
from Pepscan systems. As fluorogenic peptide substrate, Pyr-RTKR-AMC (Pyr = pyroglu-
tamic acid; AMC = 7-amino-4-methyl coumarin) was used (Bachem). ...

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