2017年6月30日星期五

The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through Tau phosphorylation

The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through Tau phosphorylation

G Mairet-Coello, J CourchetS Pieraut, V Courchet… - Neuron, 2013 - Elsevier
... early-onset form. AD is thought to be caused by the abnormal accumulation of a 40-
to 42-amino acid-long amyloid-β (Aβ) peptide derived from cleavage of the
transmembrane protein amyloid precursor protein (APP). Amyloid-β ...



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