2017年6月30日星期五

Structural and pharmacological characterization of novel potent and selective monoclonal antibody antagonists of glucose-dependent insulinotropic polypeptide …

Structural and pharmacological characterization of novel potent and selective monoclonal antibody antagonists of glucose-dependent insulinotropic polypeptide …

P Ravn, C Madhurantakam, S Kunze… - Journal of Biological …, 2013 - ASBMB
... The binding of peptides to class B receptors shows some common structural features. ... Following
this, 2.5 μl of GIP(1–42) peptide at 4 pm (an EC 80 concentration) (Bachem) was added to samples,
which were incubated for a further 30 min in order to produce an agonist ...



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