Blockade of the purinergic P2Y12 receptor greatly increases the platelet inhibitory actions of nitric oxide

Blockade of the purinergic P2Y12 receptor greatly increases the platelet inhibitory actions of nitric oxide

NS Kirkby, MH Lundberg, MV Chan… - Proceedings of the …, 2013 - National Acad Sciences

... of the inhibitory effect of DEA/NONOate when we examined either aggregation of washed platelets
induced by the glycoprotein VI (GPVI) agonist, collagen-related peptide (CRP; 1 μg/mL; Fig. S1),
or aggregation in whole blood in response to activating peptides for the thrombin ...

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