Contribution of TRPA1 as a downstream signal of proteinase-activated receptor-2 to pancreatic pain

Contribution of TRPA1 as a downstream signal of proteinase-activated receptor-2 to pancreatic pain

Y Terada, M Fujimura, S Nishimura… - Journal of …, 2013 - jstage.jst.go.jp

... A PAR2-activating peptide, infused into the pancreatic duct, caused spinal Fos expression,
which was prevented by AP18, a TRPA1 inhibitor. ... In conscious mice, acute pancreatitis was
created by 6 ip administrations of cerulein (Bachem, Bubendorf, ...

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