Ibuprofen and lipoic acid conjugate neuroprotective activity is mediated by Ngb/Akt intracellular signaling pathway in Alzheimer's disease rat model

Ibuprofen and lipoic acid conjugate neuroprotective activity is mediated by Ngb/Akt intracellular signaling pathway in Alzheimer's disease rat model

S Zara, M De Colli, M Rapino, S Pacella, C Nasuti… - Gerontology, 2013 - karger.com

... Drug Preparation Aβ(1–40) peptide (Bachem, Switzerland) was dissolved in ster- ile
saline 35% acetonitrile/0.1% trifluoroacetic acid. Both IBU and IBU-LA were solubilized
in sterile saline containing 20% (v/v) DMSO and administered ...

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