2017年6月29日星期四

Identifying natural substrates for dipeptidyl peptidases 8 and 9 using terminal amine isotopic labeling of substrates (TAILS) reveals in vivo roles in cellular homeostasis …

Identifying natural substrates for dipeptidyl peptidases 8 and 9 using terminal amine isotopic labeling of substrates (TAILS) reveals in vivo roles in cellular homeostasis …

CH Wilson, D Indarto, A Doucet, LD Pogson… - Journal of Biological …, 2013 - ASBMB
... identified from quantitative analysis of heavy/light (protease/control) isotope-labeled peptide
abundance ratios ... High and low ratio peptides were considered to be either substrates of
DP8/DP9 ... was assayed using 0.5 mm H-Ala-Pro-p-nitroanilide (Bachem, Bubendorf, Switzerland ...



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