Ligand binding to anion-binding exosites regulates conformational properties of thrombin

Ligand binding to anion-binding exosites regulates conformational properties of thrombin

MV Malovichko, TM Sabo, MC Maurer - Journal of Biological Chemistry, 2013 - ASBMB

... The peptides Hirudin(54–65) 54 GDFEEIPEEsYLQ 65 , GpIbα(269-286) DEGDTDLpYPDpY
PpYPPEEDTEG ... PAR3(44–56) 44 QNTFEEFPLSDIE 56 were synthesized by Bachem Bioscience
Inc. PAR1(49–62) 49 NDKYEPFWEDEEKN 62 was prepared by New England Peptide. ...

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