Novel agmatine dipeptide inhibitors against the West Nile virus NS2B/NS3 protease: A P3 and N-cap optimization study

Novel agmatine dipeptide inhibitors against the West Nile virus NS2B/NS3 protease: A P3 and N-cap optimization study

HA Lim, MJY Ang, J Joy, A Poulsen, W Wu… - European journal of …, 2013 - Elsevier

... Peptides containing a P1 agmatine at their C-termini have been shown to inhibit various serine
proteases, including thrombin and furin [18] and [19]. These peptidomimetics resemble peptide
aldehydes without the reactive C-terminal aldehyde functionality. ...

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