Preparing semisynthetic and fully synthetic histones h3 and h4 to modify the nucleosome core

Preparing semisynthetic and fully synthetic histones h3 and h4 to modify the nucleosome core

JC Shimko, CJ Howard, MG Poirier… - … Acetylation: Methods and …, 2013 - Springer

... as the Boc-thiazolidine-OH derivative (Bachem) to maintain stereochemistry and to allow for the
removal of N-terminal protection during cleavage. Procedure 3.5.2 carried out on the crude peptide
mixture unmasks the N-terminal Cys prior to purification. 2. Peptides may also be ...

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