The chemical synthesis of α-conotoxins and structurally modified analogs with enhanced biological stability

The chemical synthesis of α-conotoxins and structurally modified analogs with enhanced biological stability

J Banerjee, R Gyanda, YP Chang… - Peptide Modifications to …, 2013 - Springer

... 2. l-β-chloroalanine (Bachem, Bubendorf, Switzerland). ... 9. HF cleavage procedures using thiol
scavengers should be avoided to prevent premature cleavage of the peptide via thioester
exchange. As such, the “low” HF cleavage is not compatible with thioester peptides. ...

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