2019年2月21日星期四

Cysteine Substitution Reveals the Pore-Forming Region of TMC1 in Hair Cell Sensory Transduction Channels

Cysteine Substitution Reveals the Pore-Forming Region of TMC1 in Hair Cell Sensory Transduction Channels

B Pan, N Akyuz, XP Liu, Y Asai, C Nist-Lund… - Biophysical …, 2019 - cell.com
… Using precision fluid shear stress as a stimulus on a cell line overexpressing PIEZO1,
we show that Ab peptide monomers inhibit PIEZO1 at fM to pM con- centrations.
The Ab aggregates were much less potent. The effect of …


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