Product | Sox2 Antibody |
Cat# | 100-26-02A |
Unit/Weight | 100 μg |
Unit Price | $343.00 |
Species Reactivity | H, M, R, B, Sh, P, D, Rb |
Tested Application(s) | IF |
Brief Description | Rabbit Polyclonal Antibody, FITC-conjugated Antibody |
Specific Description | Transcription factor SOX-2 (Sox2) forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Defects in Sox2 are the cause of microphthalmia syndromic type 3 (MCOPS3). Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. POU5F1/OCT4, Sox2, MYC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differentiated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells. iPS cells exhibit the morphology and growth properties of ES cells and express ES cell marker genes. |
Storage | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
Peptide synthesis/Peptide Library Synthesis/Peptide Modification/Antibody Preparation Eve He eve@pepmic.com www.pepmic.com
2019年2月28日星期四
Sox2 Antibody
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