Equipotent enantiomers of cyclic opioid peptides at μ opioid receptor

Equipotent enantiomers of cyclic opioid peptides at μ opioid receptor

G Weltrowska, TMD Nguyen, NN Chung… - Peptide …, 2019 - Wiley Online Library

Head‐to‐tail cyclized analogs of the µ opioid receptor (MOR) agonist tetrapeptides DALDA
(H‐Tyr‐D‐Arg‐Phe‐Lys‐NH2 and [Dmt1] DALDA (H‐Dmt‐D‐Arg‐Phe‐Lys‐NH2; Dmt= 2′,
6′‐dimethyltyrosine) and their enantiomers (mirror‐image isomers) were synthesized and …

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