Role of the proteasome in excitotoxicity-induced cleavage of glutamic acid decarboxylase in cultured hippocampal neurons

Role of the proteasome in excitotoxicity-induced cleavage of glutamic acid decarboxylase in cultured hippocampal neurons

MS Baptista, CV Melo, M Armelão, D Herrmann… - PLoS …, 2010 - journals.plos.org

... Purified proteasome activity. To test for the activity of the purified proteasome activity, the 20S
and 26S proteasome preparations were incubated in the presence of the chymotrypsin-like
fluorogenic peptide suc-LLVY-MCA (Peptide Institute, Inc., Osaka, Japan). ...

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