2017年6月7日星期三

Development of Potent and Metabolically Stable APJ Ligands with High Therapeutic Potential

Development of Potent and Metabolically Stable APJ Ligands with High Therapeutic Potential

C Juhl, S Els‐Heindl, R Schönauer, G Redlich… - …, 2016 - Wiley Online Library
... The obtained results revealed that acylation led to a decrease in activity, which was 300-fold
lower for the Lys 8 analogue and modest for the N-terminally and Lys 9 side chain modified
peptide. These peptides were further altered by insertion of Aib at position Pro 12 that had ...


Peptide synthesis, peptide modification and peptide library synthesis, please contact:
Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com

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