Discovery of a 9-mer cationic peptide (LTX-315) as a potential first in class oncolytic peptide

Discovery of a 9-mer cationic peptide (LTX-315) as a potential first in class oncolytic peptide

BE Haug, KA Camilio, LT Eliassen, W Stensen… - 2016 - ACS Publications

... Among these peptides, LTX-315 displayed superior anticancer activity and was selected as a lead
candidate. This peptide showed relative high plasma protein binding abilities and a human plasma
half-life of 160 min, resulting in formation of nontoxic metabolites. ...

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