In vivo functional evaluation of increased brain delivery of the opioid peptide DAMGO by Glutathione-PEGylated liposomes

In vivo functional evaluation of increased brain delivery of the opioid peptide DAMGO by Glutathione-PEGylated liposomes

A Lindqvist, J Rip, J van Kregten, PJ Gaillard… - Pharmaceutical …, 2016 - Springer

... in glutathione (GSH)-coated liposomes significantly improved the brain uptake of DAMGO
(H-Tyr-D-Ala-Gly-MePhe-Gly-ol), an opioid peptide with poor brain ... The DAMGO acetate salt
(H-Tyr-D-Ala-Gly-MePhe-Gly-ol) was purchased from Bachem (Bubendorf, Switzerland). ...

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