2018年8月17日星期五

9‐Silafluorenyl Dichlorides as Chemically Ligating Coupling Agents and Their Application in Peptide Synthesis

9‐Silafluorenyl Dichlorides as Chemically Ligating Coupling Agents and Their Application in Peptide Synthesis

SJ Aspin, S Taillemaud, P Cyr… - Angewandte Chemie …, 2016 - Wiley Online Library
A fundamentally simple, mild, and practical procedure for peptide bond formation is reported
that employs a stoichiometric amount of easy‐to‐access 9‐silafluorenyl dichlorides as the
coupling agent. Without initial preactivation or elaboration of the carboxylic acid or amine …


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