In vitro biomimetic HPLC and in vivo characterisation of GM6, an endogenous regulator peptide drug candidate for amyotrophic lateral sclerosis

In vitro biomimetic HPLC and in vivo characterisation of GM6, an endogenous regulator peptide drug candidate for amyotrophic lateral sclerosis

K Valko, M Kindy, J Evans, D Ko - ADMET and DMPK, 2018 - hrcak.srce.hr

Sažetak Amyotrophic lateral sclerosis (ALS) is an idiopathic, fatal neurodegenerative
disease of the human motor system. Subunits of the 33-amino acid containing
motorneurontrophic factor (MNTF) have been investigated and GM6 has been found as a …

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