C-peptide prevents NF-κB from recruiting p300 and binding to the inos promoter in diabetic nephropathy

C-peptide prevents NF-κB from recruiting p300 and binding to the inos promoter in diabetic nephropathy

Y Li, X Li, K He, B Li, K Liu, J Qi, H Wang, Y Wang… - The FASEB …, 2018 - fasebj.org

C-peptide (CP) has demonstrated unique beneficial effects in diabetic nephropathy (DN),
but whether and how CP regulates NF-κB and its coactivator, p300, to suppress inducible
iNOS and antagonize DN are unknown. iNOS expression, NF-κB nuclear translocation …

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