[HTML] Specificity of inhibitory KIRs enables NK cells to detect changes in an altered peptide environment

[HTML] Specificity of inhibitory KIRs enables NK cells to detect changes in an altered peptide environment

P Carrillo-Bustamante, RJ de Boer, C Keşmir - Immunogenetics, 2018 - Springer

The activity of natural killer (NK) cells is tightly regulated by inhibitory and activating
receptors. Inhibitory killer immunoglobulin-like receptors (iKIRs) survey the surface of target
cells by monitoring the expression of human leukocyte antigen (HLA) class I. The binding of …

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