2018年8月15日星期三

A cell-permeant peptide corresponding to the cUBP domain of USP5 reverses inflammatory and neuropathic pain

A cell-permeant peptide corresponding to the cUBP domain of USP5 reverses inflammatory and neuropathic pain

A Garcia-Caballero, VM Gadotti, L Chen… - Molecular …, 2016 - journals.sagepub.com
Background Cav3. 2 T-type calcium currents in primary afferents are enhanced in various
painful pathological conditions, whereas inhibiting Cav3. 2 activity or expression offers a
strategy for combating the development of pain hypersensitivity. We have shown that Cav3 …


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