2018年8月11日星期六

Autophagy generates citrullinated peptides in human synoviocytes: a possible trigger for anti-citrullinated peptide antibodies

Autophagy generates citrullinated peptides in human synoviocytes: a possible trigger for anti-citrullinated peptide antibodies

M Sorice, C Iannuccelli, V Manganelli, A Capozzi… - …, 2016 - academic.oup.com
Objectives. Autophagy may represent a functional processing event that creates a substrate
for autoreactivity. In particular, autophagy may play a role in the pathogenesis of RA, since
autophagy is a key cellular event involved in the generation of citrullinated peptides, with …


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