Delivery of siRNA using lipid nanoparticles modified with cell penetrating peptide

Delivery of siRNA using lipid nanoparticles modified with cell penetrating peptide

Y Li, RJ Lee, K Yu, Y Bi, Y Qi, Y Sun, Y Li… - … applied materials & …, 2016 - ACS Publications

Clinical development of siRNA has been hindered by the lack of an effective delivery
system. Here, we report the construction of a novel siRNA delivery system, sTOLP, which is
based on cell penetrating peptide oleoyl-octaarginine (OA-R8) modified multifunctional lipid …

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