2018年8月10日星期五

[HTML] Insulin-like peptide 5 is a microbially regulated peptide that promotes hepatic glucose production

[HTML] Insulin-like peptide 5 is a microbially regulated peptide that promotes hepatic glucose production

YS Lee, F De Vadder, V Tremaroli, A Wichmann… - Molecular …, 2016 - Elsevier
Objective Insulin-like peptide 5 (INSL5) is a recently identified gut hormone that is produced
predominantly by L-cells in the colon, but its function is unclear. We have previously shown
that colonic expression of the gene for the L-cell hormone GLP-1 is high in mice that lack a …


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