2018年8月19日星期日

[HTML] Mechanism for insulin-like peptide 5 distinguishing the homologous relaxin family peptide receptor 3 and 4

[HTML] Mechanism for insulin-like peptide 5 distinguishing the homologous relaxin family peptide receptor 3 and 4

MJ Hu, XX Shao, JH Wang, D Wei, YQ Guo, YL Liu… - Scientific reports, 2016 - nature.com
The relaxin family peptides play a variety of biological functions by activating four G protein-
coupled receptors, RXFP1–4. Among them, insulin-like peptide 5 (INSL5) and relaxin-3
share the highest sequence homology, but they have distinct receptor preference: INSL5 …


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