2018年8月16日星期四

[HTML] Pulmonary targeting of adeno-associated viral vectors by next-generation sequencing-guided screening of random capsid displayed peptide libraries

[HTML] Pulmonary targeting of adeno-associated viral vectors by next-generation sequencing-guided screening of random capsid displayed peptide libraries

J Körbelin, T Sieber, S Michelfelder, L Lunding… - Molecular Therapy, 2016 - Elsevier
Vectors mediating strong, durable, and tissue-specific transgene expression are mandatory
for safe and effective gene therapy. In settings requiring systemic vector administration, the
availability of suited vectors is extremely limited. Here, we present a strategy to select …


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