2018年8月13日星期一

Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling

Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling

G Espígol-Frigolé, E Planas-Rigol, H Ohnuki… - Sci. Signal …, 2016 - stke.sciencemag.org
Interleukin-23 (IL-23), a heterodimeric cytokine composed of the unique p19 peptide (IL-
23p19) and a peptide called IL-12p40, which is shared with IL-12, is implicated in Crohn's
disease, rheumatoid arthritis, psoriasis, and other immune-mediated inflammatory diseases …


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