Identification of short hydrophobic cell-penetrating peptides for cytosolic peptide delivery by rational design
S Schmidt, MJW Adjobo-Hermans, R Kohze… - Bioconjugate …, 2016 - ACS Publications
Cell-penetrating peptides (CPPs) enhance the cellular uptake of membrane-impermeable
molecules. Most CPPs are highly cationic, potentially increasing the risk of toxic side effects
and leading to accumulation in organs such as the liver. As a consequence, there is an …
molecules. Most CPPs are highly cationic, potentially increasing the risk of toxic side effects
and leading to accumulation in organs such as the liver. As a consequence, there is an …
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