Immunohistochemical localization of the calcitonin gene-related peptide binding site in the primate trigeminovascular system using functional antagonist antibodies

Immunohistochemical localization of the calcitonin gene-related peptide binding site in the primate trigeminovascular system using functional antagonist antibodies

S Miller, H Liu, K Warfvinge, L Shi, M Dovlatyan, C Xu… - Neuroscience, 2016 - Elsevier

Calcitonin gene-related peptide (CGRP) is a potent vasodilator and a neuromodulator
implicated in the pathophysiology of migraine. It binds to the extracellular domains of
calcitonin receptor-like receptor (CLR) and receptor activity-modifying protein (RAMP) 1 that …

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