2018年8月20日星期一

New selective glucocorticoid receptor modulators reverse amyloid-β peptide–induced hippocampus toxicity

New selective glucocorticoid receptor modulators reverse amyloid-β peptide–induced hippocampus toxicity

F Pineau, G Canet, C Desrumaux, H Hunt… - Neurobiology of …, 2016 - Elsevier
In Alzheimer's disease (AD), cognitive deficits and psychological symptoms are associated
with an early deregulation of the hypothalamic-pituitary-adrenal axis. Here, in an acute
model of AD, we investigated if antiglucocorticoid strategies with selective glucocorticoid …


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