2018年8月8日星期三

Oral Administration of Peptide‐Based Drugs: Beyond Lipinski's Rule

Oral Administration of Peptide‐Based Drugs: Beyond Lipinski's Rule

GB SantosA GanesanFS Emery - ChemMedChem, 2016 - Wiley Online Library
The use of peptides in therapy presents several limitations, from physicochemical
characteristics to inadequate pharmacokinetic profiles for oral absorption. As peptides are
gaining importance in the therapeutic arsenal, there is an increasing need to rationalize the …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


没有评论:

发表评论