2018年8月18日星期六

Pharmacokinetic Properties of a Novel d-Peptide Developed to be Therapeutically Active Against Toxic β-Amyloid Oligomers

Pharmacokinetic Properties of a Novel d-Peptide Developed to be Therapeutically Active Against Toxic β-Amyloid Oligomers

LHE Leithold, N Jiang, J Post, T Ziehm… - Pharmaceutical …, 2016 - Springer
Purpose It has been shown that amyloid β (Aβ) oligomers play an important role in the
pathology of Alzheimer's disease (AD). D3, a peptide consisting solely of d-enantiomeric
amino acid residues, was developed to specifically eliminate Aβ oligomers and is …


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