The lipidated peptidomimetic Lau-[(S)-Aoc]-(Lys-βNphe) 6-NH2 is a novel formyl peptide receptor 2 agonist that activates both human and mouse neutrophil NADPH …

The lipidated peptidomimetic Lau-[(S)-Aoc]-(Lys-βNphe) 6-NH2 is a novel formyl peptide receptor 2 agonist that activates both human and mouse neutrophil NADPH …

A Holdfeldt, SL Skovbakke, M Winther, M Gabl… - Journal of Biological …, 2016 - ASBMB

Neutrophils expressing formyl peptide receptor 2 (FPR2) play key roles in host defense,
immune regulation, and in resolution of inflammation. Consequently, the search for FPR2-
specific modulators has attracted much attention due to its therapeutic potential. Earlier …

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