The new β amyloid-derived peptide Aβ1–6A2V-TAT (D) prevents Aβ oligomer formation and protects transgenic C. elegans from Aβ toxicity

The new β amyloid-derived peptide Aβ1–6A2V-TAT (D) prevents Aβ oligomer formation and protects transgenic C. elegans from Aβ toxicity

L Diomede, M Romeo, A Cagnotto, A Rossi… - Neurobiology of …, 2016 - Elsevier

One attractive pharmacological strategy for Alzheimer's disease (AD) is to design small
peptides to interact with amyloid-β (Aβ) protein reducing its aggregation and toxicity. Starting
from clinical observations indicating that patients coding a mutated Aβ variant (Aβ A2V) in …

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