Triplex-forming peptide nucleic acid probe having thiazole orange as a base surrogate for fluorescence sensing of double-stranded RNA
We have developed a new fluorescent sensing probe for double-stranded RNA (dsRNA) by
integrating thiazole orange (TO) as a base surrogate into triplex-forming PNA. Our probe
forms the thermally stable triplex with the target dsRNA at acidic pH; and the triplex formation …
integrating thiazole orange (TO) as a base surrogate into triplex-forming PNA. Our probe
forms the thermally stable triplex with the target dsRNA at acidic pH; and the triplex formation …
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Eva He
eva@pepmic.com
Pepmic Co., Ltdeva@pepmic.com
www.pepmic.com
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