Valproic acid induces NET cell growth arrest and enhances tumor suppression of the receptor-targeted peptide–drug conjugate via activating somatostatin receptor …

Valproic acid induces NET cell growth arrest and enhances tumor suppression of the receptor-targeted peptide–drug conjugate via activating somatostatin receptor …

L Sun, Q Qian, G Sun, LV Mackey… - Journal of drug …, 2016 - Taylor & Francis

Background: Human pancreatic carcinoids, a type of neuroendocrine tumors, are
asymptomatic and difficult to diagnose, with the effects of traditional anti-cancer therapies
being limited. The histone deacetylase (HDAC) inhibitor valproic acid (VPA) was evaluated …

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