[HTML] Structure of TPR domain–peptide complexes: critical elements in the assembly of the Hsp70–Hsp90 multichaperone machine

[HTML] Structure of TPR domain–peptide complexes: critical elements in the assembly of the Hsp70–Hsp90 multichaperone machine

C Scheufler, A Brinker, G Bourenkov, S Pegoraro… - Cell, 2000 - Elsevier

The adaptor protein Hop mediates the association of the molecular chaperones Hsp70 and
Hsp90. The TPR1 domain of Hop specifically recognizes the C-terminal heptapeptide of
Hsp70 while the TPR2A domain binds the C-terminal pentapeptide of Hsp90. Both …

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