2018年9月19日星期三

TLR4 Antibody

Product  TLR4 Antibody
Cat#  100-23-21A
Unit/Weight  100 μg
Unit Price  $311.00
Species Reactivity  H
Tested Application(s)  E, WB, ICC
Brief Description  (NT) Toll-like receptor
Specific Description  Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kappaB (4-6). Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis (7).
Storage  TLR4 antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

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