2018年9月20日星期四

[HTML] Peptide vaccine immunotherapy biomarkers and response patterns in pediatric gliomas

[HTML] Peptide vaccine immunotherapy biomarkers and response patterns in pediatric gliomas

S Müller, S Agnihotri, KE Shoger, MI Myers, N Smith… - JCI insight, 2018 - ncbi.nlm.nih.gov
Low-grade gliomas (LGGs) are the most common brain tumor affecting children. We recently
reported an early phase clinical trial of a peptide-based vaccine, which elicited consistent
antigen-specific T cell responses in pediatric LGG patients. Additionally, we observed …


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