TLR11 Antibody

Product	TLR11 Antibody
Cat#	100-23-16A
Unit/Weight	100 μg
Unit Price	$311.00
Species Reactivity	M
Tested Application(s)	E, WB, ICC
Brief Description	(IN) Toll-like receptor protein
Specific Description	Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7).
Storage	TLR11 antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.