An MD2-derived peptide promotes LPS aggregation, facilitates its internalization in THP-1 cells, and inhibits LPS-induced pro-inflammatory responses

An MD2-derived peptide promotes LPS aggregation, facilitates its internalization in THP-1 cells, and inhibits LPS-induced pro-inflammatory responses

A Tandon, MK Harioudh, N Ishrat, AK Tripathi… - Cellular and Molecular …, 2018 - Springer

Abstract MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and
binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).
Internalization of pathogen inside the mononuclear phagocytes has also been attributed to …

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