2018年9月12日星期三

LEAP‐1, a novel highly disulfide‐bonded human peptide, exhibits antimicrobial activity

LEAP‐1, a novel highly disulfide‐bonded human peptide, exhibits antimicrobial activity

A Krause, S Neitz, HJ Mägert, A Schulz… - FEBS …, 2000 - Wiley Online Library
We report the isolation and characterization of a novel human peptide with antimicrobial
activity, termed LEAP‐1 (liver‐expressed antimicrobial peptide). Using a mass spectrometric
assay detecting cysteine‐rich peptides, a 25‐residue peptide containing four disulfide bonds …


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