Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
JM Kilby, S Hopkins, TM Venetta, B DiMassimo… - Nature medicine, 1998 - nature.com
T-20, a synthetic peptide corresponding to a region of the transmembrane subunit of the HIV-
1 envelope protein, blocks cell fusion and viral entry at concentrations of less than 2 ng/ml in
vitro. We administered intravenous T-20 (monotherapy) for 14 days to sixteen HIV-infected …
1 envelope protein, blocks cell fusion and viral entry at concentrations of less than 2 ng/ml in
vitro. We administered intravenous T-20 (monotherapy) for 14 days to sixteen HIV-infected …
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