A rat model of oligomeric forms of beta-amyloid (Aß) peptide: neuronal loss, synaptic alteration, astrogliosis, and calcium-binding proteins activation in vivo

A rat model of oligomeric forms of beta-amyloid (Aß) peptide: neuronal loss, synaptic alteration, astrogliosis, and calcium-binding proteins activation in vivo

A Gonzalo-Ruiz, M Delso, I Carrero… - European Journal of …, 2019 - eurjanat.com

Oligomers of Beta-amyloid (Aß) peptide are presumed to cause synaptic and cognitive
dysfunction in Alzheimer's disease (AD). However, their contribution to other pathological
features of AD remains unclear. To address the latter, we applied microinjections of Aß1-42 …

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