Insulin inhibits Aβ fibrillogenesis through a decrease of the GM1 ganglioside‐rich microdomain in neuronal membranes

Insulin inhibits Aβ fibrillogenesis through a decrease of the GM1 ganglioside‐rich microdomain in neuronal membranes

N Yamamoto, H Taniura, K Suzuki - Journal of neurochemistry, 2010 - Wiley Online Library

... The bovine brain GM1, (±)-threo-1-phenyl-2-decanoylamine-3-morpholino-1-propanol
hydrochloride (PDMP) and chloroquine were obtained from Wako (Osaka, Japan). Synthetic
Aβ1-40 was purchased from Peptide Institute (Osaka, Japan). Cell culture. ...

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