Development of novel ligands for peptide GPCRs

Development of novel ligands for peptide GPCRs

BM Moran, AM McKillop, FPM O'Harte - Current opinion in pharmacology, 2016 - Elsevier

Incretin based glucagon-like peptide-1 receptor (GLP-1R) agonists which target a G-protein
coupled receptor (GPCR) are currently used in the treatment of type 2 diabetes. This review
focuses on GPCRs from pancreatic β-cells, including GLP-1, glucose-dependent …

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